Research Suggests Stepping Up Daily Activity Can Slow Alzheimer's Progression
A recent 14-year study has found that even modest amounts of daily exercise, such as walking at least 3,000 steps per day, may slow the progression of Alzheimer's disease in older adults. The research, published in Nature Medicine, analyzed data from over 300 participants aged 50 to 90 who were initially cognitively unimpaired.
According to the study, those who walked between 3,000 and 5,000 steps per day experienced a delay of three years in cognitive decline, while those who managed 5,000 to 7,000 steps daily saw a delay of seven years. The findings suggest that even a relatively small amount of physical activity may have a significant impact on brain health.
The researchers found that individuals with elevated levels of amyloid protein, a toxic substance associated with Alzheimer's disease, who were physically active, had slower rates of cognitive decline and reduced buildup of tau protein in the brain. Conversely, sedentary individuals saw a substantially faster rate of cognitive decline and amyloid buildup.
While the study cannot rule out reverse causation, where early Alzheimer's symptoms may lead to decreased physical activity, the data suggests that exercise is indeed protective. Further research is needed to confirm the findings and explore potential mechanisms behind the observed effects.
Experts are hailing the study as a significant step forward in understanding the relationship between physical activity and brain health. Dr. Julia Dudley from Alzheimer's Research UK noted that even a modest amount of walking, around 5,000 steps per day, can help slow down the buildup of tau protein, a key driver of Alzheimer's disease.
The study's lead author, Dr. Wai-Ying Yau, emphasized the importance of building sustained habits to protect brain health. "We're encouraging older people who are at risk of Alzheimer's to make small changes to their activity levels... Every little bit counts," she said.
With over 50 million people worldwide affected by dementia and 500,000 in the UK alone, this research highlights the potential for simple lifestyle changes to support brain health and slow disease progression.
				
			A recent 14-year study has found that even modest amounts of daily exercise, such as walking at least 3,000 steps per day, may slow the progression of Alzheimer's disease in older adults. The research, published in Nature Medicine, analyzed data from over 300 participants aged 50 to 90 who were initially cognitively unimpaired.
According to the study, those who walked between 3,000 and 5,000 steps per day experienced a delay of three years in cognitive decline, while those who managed 5,000 to 7,000 steps daily saw a delay of seven years. The findings suggest that even a relatively small amount of physical activity may have a significant impact on brain health.
The researchers found that individuals with elevated levels of amyloid protein, a toxic substance associated with Alzheimer's disease, who were physically active, had slower rates of cognitive decline and reduced buildup of tau protein in the brain. Conversely, sedentary individuals saw a substantially faster rate of cognitive decline and amyloid buildup.
While the study cannot rule out reverse causation, where early Alzheimer's symptoms may lead to decreased physical activity, the data suggests that exercise is indeed protective. Further research is needed to confirm the findings and explore potential mechanisms behind the observed effects.
Experts are hailing the study as a significant step forward in understanding the relationship between physical activity and brain health. Dr. Julia Dudley from Alzheimer's Research UK noted that even a modest amount of walking, around 5,000 steps per day, can help slow down the buildup of tau protein, a key driver of Alzheimer's disease.
The study's lead author, Dr. Wai-Ying Yau, emphasized the importance of building sustained habits to protect brain health. "We're encouraging older people who are at risk of Alzheimer's to make small changes to their activity levels... Every little bit counts," she said.
With over 50 million people worldwide affected by dementia and 500,000 in the UK alone, this research highlights the potential for simple lifestyle changes to support brain health and slow disease progression.